News
Find out about what's been happening in the trial.

Christmas Message 2024
Dec 2024: A Christmas message

Interim Analysis Stage 1 – Amantadine – Results
Dec 2024: The Stage 1 interim analysis for amantadine has taken place and the trial committees have decided to continue testing amantadine.

Mr Stevie Morris
Dec 2024: Remembering Mr Stevie Morris for his advocacy and invaluable contributions to MND-SMART through his work as a Patient Advisory Group member.

Memantine, Trazodone and Contemporaneous Placebo – An Unblinding Update
Dec 2024: Final database lock for the discontinued memantine, trazodone and contemporaneous placebo arms has been completed. Former trial participants randomised to these arms can now be unblinded to their treatment allocation.

First results published from innovative platform trial, MND-SMART, aiming to speed up delivery of treatments for motor neuron disease
Sep 2024: Trazodone and memantine results published

Welcome to Sheffield, King's College London and Brighton
Jan 2024: Sheffield, King's College London, and Brighton have recently joined MND-SMART.

Christmas Wishes 2023
Dec 2023: A Christmas video message

Autumn 2023 Newsletter
Nov 2023: Our latest newsletter is now available.

Factors Impacting Trial Participation in People with MND
Oct 2023: MND-SMART researchers have recently published a study that aimed to improve understanding of why people with MND choose to participate, or not participate, in clinical trials of potential new treatments.

The role of placebo control in clinical trials for neurodegenerative diseases
Oct 2023: The MND-SMART trial team, and the people living with MND who are co-producing the trial, have considered the pros and cons of including a placebo group in a trial like MND-SMART.

New funding to accelerate opportunities for participation in MND-SMART
Sep 2023: We're delighted to announce that the Alan Davidson Foundation has pledged £1.275M investment in MND-SMART over 5 years to further increase opportunities for people living with MND across the UK to participate in the trial.

Breaking News: An update on Memantine, Trazodone and Placebo arms
Sep 2023: Judy Newton, MND nurse consultant and Beverley Gray, MND-SMART family, and participant representative detail the outcome of the latest results of MND-SMART.