News

Find out about what's been happening in the trial.

The MND-SMART Davidson Nurses pictures with the Davidson Trustees

MND-SMART launches ‘Davidson Nurses’ programme to expand access to MND Research

Mar 2025: Aligned in our commitment to improve access to research for people living with motor neuron disease, MND-SMART and the Alan Davidson Foundation celebrated a landmark collaboration with the official launch of the ‘Davidson Nurses’ programme.

Christmas Message 2024

Dec 2024: A Christmas message

Interim Analysis Stage 1 – Amantadine – Results

Dec 2024: The Stage 1 interim analysis for amantadine has taken place and the trial committees have decided to continue testing amantadine.

Stevie Morris, MND-SMART Patient Advisory Group member and his wife Mary.

Mr Stevie Morris

Dec 2024: Remembering Mr Stevie Morris for his advocacy and invaluable contributions to MND-SMART through his work as a Patient Advisory Group member.

Memantine, Trazodone and Contemporaneous Placebo – An Unblinding Update

Dec 2024: Final database lock for the discontinued memantine, trazodone and contemporaneous placebo arms has been completed. Former trial participants randomised to these arms can now be unblinded to their treatment allocation.

a screenshot of the title of the MND-SMART publication on the stage 2 interim analysis for memantine and trazodone, published in the lancet neurology

First results published from innovative platform trial, MND-SMART, aiming to speed up delivery of treatments for motor neuron disease

Sep 2024: Trazodone and memantine results published

A picture of Dr Andrew Barritt, Principal Investigator and colleague Daniel Hansen, Lead Research Nurse from the Brighton team. Both are smiling at the camera and are standing in a clinic room.

Welcome to Sheffield, King's College London and Brighton

Jan 2024: Sheffield, King's College London, and Brighton have recently joined MND-SMART.

Christmas Wishes 2023

Dec 2023: A Christmas video message

Autumn 2023 Newsletter

Nov 2023: Our latest newsletter is now available.

screenshot of publication titles and authors from Journal of Neurology

Factors Impacting Trial Participation in People with MND

Oct 2023: MND-SMART researchers have recently published a study that aimed to improve understanding of why people with MND choose to participate, or not participate, in clinical trials of potential new treatments.

A screenshot of the header of the publication in the scientific journal

The role of placebo control in clinical trials for neurodegenerative diseases

Oct 2023: The MND-SMART trial team, and the people living with MND who are co-producing the trial, have considered the pros and cons of including a placebo group in a trial like MND-SMART.

A group of 12 people standing and smiling outside the Anne Rowling Regenerative Neurology Clinic. Half of the people are researchers wearing teal scrubs. The others are the trial leads for MND-SMART and representatives from the Alan Davidson Foundation.

New funding to accelerate opportunities for participation in MND-SMART

Sep 2023: We're delighted to announce that the Alan Davidson Foundation has pledged £1.275M investment in MND-SMART over 5 years to further increase opportunities for people living with MND across the UK to participate in the trial.