News
Find out about what's been happening in the trial.
Amantadine Stage 2 Interim Analysis Results
The results of the second interim analysis have been released.
MND SMART Launches in Imperial College Healthcare NHS Trust
Oct 2025: The trial opens a new recruitment location in Imperial College Healthcare NHS Trust.
The MND SMART Gathering 2025
Sep 2025: MND SMART annual investigators meeting
MND-SMART launches in Hull Royal Infirmary
Sep 2025: Hull Royal Infirmary Joined the MND-SMART team.
50 participants randomised at the Southampton trial centre!
Jul 2025: The research team at the Southampton General Hospital trial centre have randomised more than 50 participants.
Fourth investigational arm launched in MND-SMART
Jun 2025: A fourth drug, tacrolimus, has recently been launched in MND-SMART.
MND-SMART Opens in York and Scarborough Hospitals
Jun 2025: York and Scarborough Hospitals are the newest centres to open recruitment to MND-SMART!
MND-SMART launches ‘Davidson Nurses’ programme to expand access to MND Research
Mar 2025: Aligned in our commitment to improve access to research for people living with motor neuron disease, MND-SMART and the Alan Davidson Foundation celebrated a landmark collaboration with the official launch of the ‘Davidson Nurses’ programme.
Christmas Message 2024
Dec 2024: A Christmas message
Interim Analysis Stage 1 – Amantadine – Results
Dec 2024: The Stage 1 interim analysis for amantadine has taken place and the trial committees have decided to continue testing amantadine.
Mr Stevie Morris
Dec 2024: Remembering Mr Stevie Morris for his advocacy and invaluable contributions to MND-SMART through his work as a Patient Advisory Group member.
Memantine, Trazodone and Contemporaneous Placebo – An Unblinding Update
Dec 2024: Final database lock for the discontinued memantine, trazodone and contemporaneous placebo arms has been completed. Former trial participants randomised to these arms can now be unblinded to their treatment allocation.