News

Find out about what's been happening in the trial.

Research Nurses Rolan, Alida and Kat from the Southampton trial centre

Jul 2025: 50 participants randomised at the Southampton trial centre!

The research team at the Southampton General Hospital trial centre have randomised more than 50 participants.

A group photo of many of the people working together to deliver MND-SMART at the 2024 Investigators Gathering in Edinburgh. Picture is taken outside, with a view of Edinburgh castle in the background.

Fourth investigational arm launched in MND-SMART

Jun 2025: A fourth drug, tacrolimus, has recently been launched in MND-SMART.

MND-SMART Opens in York and Scarborough Hospitals

Jun 2025: York and Scarborough Hospitals are the newest centres to open recruitment to MND-SMART!

The MND-SMART Davidson Nurses pictures with the Davidson Trustees

MND-SMART launches ‘Davidson Nurses’ programme to expand access to MND Research

Mar 2025: Aligned in our commitment to improve access to research for people living with motor neuron disease, MND-SMART and the Alan Davidson Foundation celebrated a landmark collaboration with the official launch of the ‘Davidson Nurses’ programme.

Christmas Message 2024

Dec 2024: A Christmas message

Interim Analysis Stage 1 – Amantadine – Results

Dec 2024: The Stage 1 interim analysis for amantadine has taken place and the trial committees have decided to continue testing amantadine.

Stevie Morris, MND-SMART Patient Advisory Group member and his wife Mary.

Mr Stevie Morris

Dec 2024: Remembering Mr Stevie Morris for his advocacy and invaluable contributions to MND-SMART through his work as a Patient Advisory Group member.

Memantine, Trazodone and Contemporaneous Placebo – An Unblinding Update

Dec 2024: Final database lock for the discontinued memantine, trazodone and contemporaneous placebo arms has been completed. Former trial participants randomised to these arms can now be unblinded to their treatment allocation.